RNA-triggered gene silencing.
نویسنده
چکیده
Double-stranded RNA (dsRNA) has recently been shown to trigger sequence-specific gene silencing in a wide variety of organisms, including nematodes, plants, trypanosomes, fruit flies and planaria; meanwhile an as yet uncharacterized RNA trigger has been shown to induce DNA methylation in several different plant systems. In addition to providing a surprisingly effective set of tools to interfere selectively with gene function, these observations are spurring new inquiries to understand RNA-triggered genetic-control mechanisms and their biological roles.
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ورودعنوان ژورنال:
- Trends in genetics : TIG
دوره 15 9 شماره
صفحات -
تاریخ انتشار 1999